Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets
This seems highly likely, especially as it has been shown that in several systems mutations affecting
Attempts have been made from a study of the changes produced by mutation to obtain the relative order