We can and should complain about certain horrors of the modern world, but when it comes to the treatment of mental illness, the advances made in the last hundred years have been far more significant than the space program, nuclear fission, or even The Wire, for so many fortunate people.
A long-term relationship is about showing up and working hard and banking on each other. If one's down, the other might be up and can help the other one up, and sometimes you're both down and you just [band] together. Endurance is a big theme of it for me. That might not sound romantic, but I kind of think that it is.
The danger for a comedian on Twitter is the same danger that any civilian faces: sometimes you gotta put that phone down and go live your life. When you're on Twitter, you're not living, and if you're not living, you're not taking in stimuli with which you can create new material.